After recently been dumped Tom hasn't been out for years. His best friends Bruce and Cal decide to throw him back into the dating game, regardless of how he feels about it. The first date is set with Maya, an beautiful, brutal attorney that reduces Tom to tears.
After a chance meeting outside of the bar, the sweet and innocent Liv is charmed by the sophisticated Brit, Ron, and the two have instant chemistry. Meanwhile, Jessica and her frenemy Fab, start a friendly competition to win the affections of Dominic, the very hot bartender. Tom, Bruce and Cal are still on the hunt for some ladies, and even though Tom is smitten over Maya, he shockingly comes through and takes one for the team.
Bruce is as abrasive as they come and when he sets his eyes on Jessica, a single mom from New Jersey, he thinks she's easy prey. He's very quickly rejected, but he ignores Tom and Cal's advice to abort the mission and he continues to pursue her. Meanwhile, Liv decides to indulge her curiosity with Ron, but that leads to some unexpected trouble.
Hopeless romantics and frequently heart-broken, Cal and Kacey seem perfect for each other, but Bruce has other ideas and tries to keep his friend from being a four time loser in love. Liv's wild night continues as she decides to give her panties to Ron while Jessica and Fab decide to engage in a friendly competition.
Jessica and Fab compete for Dominic, the bartender. Bruce, Cal and Tom can no longer get any service from Kacey, who is upset with Cal, so the guys risk giving up their table to move to a booth. Liv is shocked when she learns something intimate about Ron.
Tom and Maya are hitting it off well, to the amazement of Bruce and Cal when trouble enters the bar in the form of Tom's ex-girlfriend. Liv makes friends with Jessica and Fab and asks for their advice with meeting guys. A group of firemen enter the bar and charm the ladies but Ron is in no mood to surrender.
Bruce and Fab's intense dislike of each other lead to a bizarre bonding moment. Tom becomes the talk of bar and gains respect by accident. Liv and Maya track down the owner of a picture of a well endowed package.
Jessica regrets sending a naked photo to Ron and sets out to get him to delete it. Meanwhile, Liv complicates things between Jessica and Ron and Maya hits it off with an attractive guy who gives her an offer she can't refuse. The chance to hook up is in Bruce's favor when he meets a woman who is into redheads, but things quickly begin to look grim when a famous redhead enters the bar.
After countless meaningless hookups, Kacey confronts Dominic about their relationship status. Dominic then finds himself in unfamiliar territory and turns to Tom of all people for advice. Meanwhile, Maya and Fab try to help a drunken Liv, who has been knocking back drinks all night, after they spot a flock of bar vultures eyeing her. And the chance of hooking up with someone is being hampered for Bruce and Cal as they fend off a table interloper.
Liv is forced to face the reality of her actions when her fiancee unexpectedly shows up at the bar. Meanwhile, Bruce gets into a bar-gument with Tom and Cal after he finds out they watched the third season of 'Downton Abbey' without him. Bruce takes offense and finds a new group of guys to hang out with, but when they also start to call him out for being a terrible person, he ponders whether or not he owes Tom and Cal an apology.
The night is drawing to a close and nobody wants to go home alone once it's last call. Bruce recruits Maya to fake flirt with him to get Jessica's attention, but when things start to look like they're getting serious between them, Tom gets nervous causing Cal to spring into action. Meanwhile, Fab spots her attractive gynecologist and debates whether or not she'd be able to date him.
The bartenders have spoken and it's last call at Mix. Bar tabs aren't the only things that need to be closed as Tom finds himself bonding with Liv while she tries to help him take home Maya. But in the process, Liv and Tom can't help but realize they might actually be meant for each other instead. Bruce starts to panic when he realizes Jessica is probably going to go home with Dominic, so he sets out to find a backup girl he can take home but learns some things aren't always what they appear.
The night is coming to an end and it's Tom's last chance to ask Maya to go home with him, but Bruce and Cal explain the various obstacles that lie ahead that could prove costly on his quest to find love. Meanwhile, Bruce has to decide whether or not to make a final play for Jessica or go home with a girl who is infatuated with his red-headed attributes. Across town, Liv finds herself in a situation with Ron that comes down to a last minute decision that will ultimately affect her happiness. And Kacey will need to overlook some information she learns about Cal and decide if she still wants to keep her date with him.