After he is diagnosed with Parkinson's, NYC anchorman Mike Henry put his life on hold for five years. But now he is getting restless. All his old boss Harris Green has to do is get him to come back and convince Mike that it was his idea all along. To succeed, Harris teams up with Mike's family, who are eager to get him out of the house.

Mike tries to deal with an attractive yet noisy upstairs neighbor, who develops a crush on him. Meanwhile, Ian tries to court Eve's new friend at school, and Leigh enjoys being mistaken for a single mom and decides to take advantage of it.

When Mike and Annie learn that Graham's after school program has been cancelled, the two compete over finding a new activity for him to enjoy. Meanwhile, at work, Mike is reunited with his nemesis, Susan Rodriguez-Jones, when Harris brings her on as the new anchor at NBC4. Back at home, Leigh and Ian accidentally engage in a Twitter war with a girl at Eve's school.

Annie learns that Mike has apologized to a stranger for her hot-headed behavior and demands that he be more of a "team player". Harris hosts an office karaoke party. Leigh adopts a puppy with good intentions, but Eve is left in charge. Meanwhile, Ian, still stuck in Graham's tiny old bedroom, tries to convince his brother to switch back.

Mike's plan to get closer to Eve by getting her an internship at the station backfires when she appears to idolize his nemesis, Susan Rodriguez-Jones. Inspired by Eve's internship, Ian decides to hire an intern himself for his Internet start-up. Meanwhile, Annie struggles with how to give Leigh honest notes on her young adult novel.

Annie learns that Mike has apologized to a stranger for her hot-headed behavior and demands that he be more of a "team player". Harris hosts an office karaoke party. Leigh adopts a puppy with good intentions, but Eve is left in charge. Meanwhile, Ian, still stuck in Graham's tiny old bedroom, tries to convince his brother to switch back.

Mike and Annie try to have a romantic weekend away at a charity golf tournament that Mike is playing in. While they're gone, Ian and Eve rent out the apartment to make some extra cash. After Leigh's date cancels on her, she has a "date night" with Graham.

Mike's love for his sister, Leigh, is put to the test when a bed bug infestation forces her to move in with his family. At the same time, Mike prepares for a big interview at work with special guest star Governor Chris Christie. Eve has trouble getting out of a practical joke she's played on her brother Ian.

Ian attends homecoming at his girlfriend's high school, prompting Mike to discuss college with him. Meanwhile, Annie is hurt to learn that Eve confides in Leigh and not her; and Graham retaliates when his parents decide to clean up some clutter.

When Mike and Leigh's parents come to town for Thanksgiving, Mike struggles to have an honest conversation with his father, while Annie deals with Mike's controlling mother. Eve teams up with Harris to keep tradition alive in the Henry household.

Mike and Annie's awesome gift exchange hits a snag when Mike learns he has to anchor the news on Christmas Eve. Ian tries to keep the magic of Christmas alive for Graham. After attending a friend's Hanukkah celebration, Eve becomes intrigued by the ideals of Judaism.

Mike throws a party to celebrate Harris winning a big award. Meanwhile, when Annie throws Graham a "safe" slumber party, Eve and Ian try to distract her to make sure the kids have a good time. Leigh makes use of Harris's party limo to go to IKEA.

When Mike is scooped on a story about Jared Norwood, a mobster living in his own building, he starts to worry he's off his game. Ian and Eve discover Norwood gave Graham a statue, and they fight with Graham over what to do with it. Meanwhile, Leigh and Harris try to keep their new relationship a secret from the Henry family.

Mike and Annie work hard to maintain some friends. Meanwhile, Eve pretends to be edgy to impress a boy; and Ian fears that Graham no longer admires him.

Mike faces off with Susan to cover the Winter Olympics in Russia. Meanwhile, Eve becomes a beauty-pageant contestant; and Leigh suspects that a ghost looking for romance is haunting her apartment.