Dr. Emmet Cole, beloved adventurer and television personality goes missing deep in the Amazon. After a fruitless search for him, his family and friends abandon hope and hold a memorial service to commemorate his amazing life. His grieving wife, Tess, reluctantly tries to face the reality that her husband is gone, while her son, Lincoln, is more than ready to bury his past. Six months later Emmet's location beacon mysteriously begins to relay a signal.

When the spirit of Dr. Emmet Cole mysteriously enters Jahel, the message is clear, go home! Instead, Tess determines to go into the jungle to find clues to Cole's whereabouts. While on their mission, they discover a tree draped in children's dolls that they suspect is there to ward off the "spirit of the abandoned girl" who drowned in the river.

When the whole crew of the Magus goes blind due to spores from a tree, lone holdout AJ will have to overcome his most paralyzing fear to find a cure before the blindness becomes permanent. Meanwhile, the local Morcego tribe stalks the crew and judges whether they are worthy to stay in the jungle. If they are deemed unworthy, the consequences could be fatal.

As the search continues for Emmet and his crew, the Magus comes across one of Emmet's crew members who went missing alongside Emmet. They soon discover that he's been cursed and learn the mystical story behind the curse, which is now a matter of life and passing. Lincoln faces a challenge when the rest of the crew want to leave their plagued colleague behind to continue the mission, and he must try to be their moral compass.

The Magus crew are run aground by another vessel, and soon learn that the seemingly welcoming crew members of a ship claiming to have come to their rescue have in fact a very different agenda, causing a dire, life-and-passing situation. The crew also make a shocking discovery that will leave one of them in tears.

The Magus crew continue their trek to the Sahte Falls where they discover Emmet's camera bag. Upon further examination of the tapes within it, they find some powerful footage of Emmet that shows him spiraling out of control, and it leads the crew further into the Amazon. Meanwhile, Lena reveals a secret she's been carrying to a fellow crew member.

The Magus crew find themselves in a stark predicament as they're stalked by a cannibalistic terror while searching through an abandoned research facility following mysterious clues that suggest Dr. Emmet Cole may still be alive. Meanwhile, security force leader Kurt is forced to make a heavy personal sacrifice when it comes to the safety of the crew.

With a course now plotted for their final destination, the Magus crew suddenly finds itself in complete chaos when a member of their own is shot dead, leading Jahel to call upon the spirit of the Boiúna to help, against the wishes of her father. The crew's quest is threatened further by the unknown hugger, as the situation continues to spiral out of control