IR receives a distress call from the Calypso, a space vessel returning from a long mission. Scott and Virgil get aboard the plummeting ship and locate the disoriented crew along with an old robot named Braman, who sent the original distress call.
In the 21st century, Jeff Tracy, a former astronaut, amasses a colossal fortune and decides that he must use it to benefit others. His answer to this desire is to create International Rescue, a unique private emergency response service equipped with customized designed vehicles and equipment that enable the organization to react to any crisis whether it be in sea, air, land, or space.
Jeff's five sons volunteer to operate as the pilots and field agents, as well "Brain" who acts as the teams engineer. In addition, Jeff's friend, Kyrano and his daughter Tanusha aka Kayo agree to be the support staff. In addition to the field team, IR also maintains an intelligence network with Lady Penelope and her ex-con chauffeur, Parker as the chief agents in this arm.