Steven and Samantha Bloom, formerly two of the CIA's best spies, are reinstated when a good friend goes missing.
When a private security detail in Pakistan cuddles the scientists they're paid to protect and kidnaps the lead scientist, CIA handler Shaw sends married spies Steven and Samantha to the rescue.
When an informant claims to have information on a codebreaking device that would compromise the identities of every agent in the CIA, Shaw sends Steven and Samantha to Berlin to verify the man's claims. When the informant ishuged, the duo meets with Hoyt and Leo to check out the allegations. As the team travels throughout the city, they are surprised to learn that the device isn't as it seems. Amidst the danger around them, Steven and Samantha struggle to find the balance between being partners and husband and wife while out in the field. Back in Los Angeles, Lizzy connects with a man while catering his father's funeral
Steven and Samantha travel to Ireland and then England in their endeavor to find a very important CIA hard drive, which has gone missing.
Steven and Samantha are assigned with finding and instigating the defection of a North Korean Physicist, who has invented a device capable of changing an object's matter.
After renowned weapons dealer, Xerxes, hides the formula to a dangerous and lethal biological weapon in a painting, Shaw assigns Steven and Samantha the task of traveling to Tuscany to secure the painting and capture Xerxes.
Steven, Samantha and Leo get orders from Shaw to take on a mission in Lima, Peru where an sleepytime plot has been orchestrated against president-elect Alberto Loya. When Samantha gets too emotionally invested, she puts the whole mission at stake and her own life in danger. Elsewhere, Lizzy caters a party for Samantha's college friend and also discovers a connection with an unlikely source.
When a plane disappears off the radar and its pilot is nowhere to be found, it's up to Steven and Samantha to locate the man and the dangerous bomb he has with him. Traveling to Russia, the Blooms team with Hoyt and meet with some unexpected challenges and a wounded comrade in their quest to complete their dangerous mission.
When Leo wakes up in a hotel in Mexico with a dead woman next to him and no memory of what transpired, Steven, Samantha and Hoyt travel south of the border in hopes of putting the pieces together to prove Leo's innocence. The stakes get even higher when Shaw unexpectedly arrives with news of a dangerous terrorist on the loose.
When American currency plates are stolen from an armored truck, Steven and Samantha must recover them before the terrorist who stole them counterfeits American money. Traveling to Croatia, the situation gets complicated when the Blooms find themselves working together with Steven's estranged brother Gary. Meanwhile, Leo helps Lizzy make an important decision about her future
Just when Steven and Samantha have settled into their romantic Greek vacation, Shaw pulls them away to lend their assistance to an escalating situation in Tel Aviv, where terrorists have seized a hotel and taken hostages. Going undercover with help from Hoyt, the duo soon realizes their mission involves much more than they were told.