Xander tries to use Valentines Day to further his relationship with Cordelia but she succumbs to peer pressure and breaks up with him. With the help of Amy (who is exploring her mother's witch powers), he puts a love spell on her which goes horribly wrong, turning him into every woman's desire; except Cordelia's.

When Dawson finds out about his mother's affair and Joey's knowledge of it, Dawson feels betrayed by both of them. Seeking solace he turns to Jen to talk with, but learns more than he bargained for about her own past digressions - and the true reason she moved to Capeside. Meanwhile Pacey and Tamara's fling gets more involved and intimate

In this scientific mystery, NOVA ventures to the front lines of medical research where scientists are scrambling to understand the strange new ailment popularly known as "mad cow disease". Highly infectious and incurable, this disease has claimed the lives of nearly a million cattle in Britain, and a variant is responsible for a handful of deaths in humans. Millions more people may have been exposed, and now the race is on to determine if we are on the brink of another deadly epidemic like AIDS or Ebola. What scientists are finding is making them rethink many fundamental assumptions about epidemiology and may hold startling implications for public health in the future.

We see the action from the viewpoint of two maintenance workers as a race of savage aliens attacks the station.