Emma tries to help her drug addicted sister and learns that local addicts are exhibiting strange mutations linked to tainted heroin.

It's Sabrina the Grinch, increasingly grumpy in the face of her aunts' unflagging efforts to get her into the holiday spirit.

Penny and Josh are driving a patient back to Holby when a car ends up running a red light causing a crash as Duffy learns that Frank has run of with stolen jewellery.