The remaining nine teams took off from their Pit Stop in a lakeside village in Amsterdam and were instructed to fly Ouagadougou, Burkina Faso in Africa. Upon arrival, the teams took taxis to the area train station, where a long wait for a morning train allowed them to mingle and have fun. The teams then took a train to Bingo in the middle of the African Savannah, where they were faced with a Roadblock. This challenging Roadblock forced one member of each team to deal with camels, a task that proved extremely frustrating for one racer in particular. Upon completing the task, they then led a group of four camels along a marked path. Several teams were forced to backtrack after going in the wrong direction, leading one racer to admit that their partner is better at navigation. Once the teams reached the cluebox at the end of the correct path, they were presented with a Detour. Ultimately, one team that had struggled was able to just make it ahead of another to the Pit Stop on the outskirts of Bingo, causing another team to be eliminated.

Marge starts up a new women-only gym in Springfield and Homer frets about losing her after she becomes a highly successful businesswoman. Meanwhile, Coolsville, a new comic book shop, opens up in Springfield and puts Comic Book Guy out of business.

Declan gets a new assignment from the FBI. Eileen is in for a shock when she becomes a volunteer at social services. Tommy is feeling pressure to become Judd's replacement as chairman of a committee. Michael and Collin enter a partnership with Nozzoli.

The first wedding of the show takes place at The Blue Antelope where Katie helps Jo to make arrangements. Katie discovers a secret about Oliver's father which pushes him away from her. Danny encounters a sick elephant, he asks Tumelo to help. It turns out that the sick elephant is in love with a giraffe.

After Hank falls in love with organic food he starts his own mini co-op garden in his back yard.

Kourtney, Kim and Khloé are about to leave to Las Vegas when Kourtney has a pregnancy scare. Meanwhile, Kendall & Kylie ask their dad for a puppy, and he says no, but Kris goes behind his back and buys them a puppy anyway, which makes him upset, as he feels like Kris never lets him make decisions.

While playing poker with the guys, Stan is found to be a virgin. Not in the traditional way, but in that he's never killed anyone. Roger and the guys help Stan bust his killing cherry.

The team re-opens the 1963 case of teenage girl who was then thought to have committed suicide. Now, new evidence leads them to believe the girl might have been murdered for acting and dressing like a boy.

Peter starts an anti-immigration group; however, he quickly changes his mind when he finds out that he was born in Mexico. Unable to prove his citizenship, pass the naturalization test or convince investigators that his marriage to Lois is for real, he ends up working for Carter as a landscaper, all the while fighting for immigration rights.

While trying to find an arsonist responsible for claiming the life of a firefighter, Sebastian's team finds that the man the firefighter died trying rescue was murdered before the fire began.

Dexter is attacked by the man who murdered his mother. Meanwhile, Lila wants to get closer to Dex, and Debra and Lundy close in on the Bay Harbor Butcher.