Thirteen receives treatment by Foreman while taking part in his clinical trial on Huntington's Disease.

Kyle fears for Amanda's life after a psychic gives him a stark warning.

The students are stressed out as they find out who was accepted and who didn't make the cut for early admission to Yale. Meanwhile, Serena bonds with Rachel, her Shakespeare teacher, who is unaware of what Blair has in store for her following receiving her first B; Chuck finds an unlikely ally in his feud wtih Jack; and Nate and Vanessa have a romantic evening together.

Looking to get friendly with Barry Kripke to gain access to a piece of high-tech lab equipment, Sheldon develops a flowchart process to make friends.

Brent has to prove that he really is a Roughriders fan after failing to keep up his end of a pact; Wanda learns the unwritten rules of making a mixed CD; Karen takes up reading to seniors, which has an unexpected effect on Oscar.

Amaar is enlisted by a friend to go on a double date but finds his confidence somewhat shaken by the outcome.

Alton explores various sweet uses of the spice, ginger.

Ricky's father comes to town with some advice for him on how to be a parent.

There are 12 remaining ladies, in which 10 will be going on a date with Jason. Eight of the women will accompany him to the Keep-A-Breast Foundation, while two others get a one-on-one date. (One is a single mom who brings her kid along to Legoland, and the other takes a helicopter ride over Hoover Dam and a private concert with Kate Voegele). One of the dates ends horribly, while another runs off during the rose ceremony. At the end of the day, the field is reduced to nine.

Lily comes back from a trip to Seattle only to run into a blizzard, which may threaten an airport ritual of meeting Marshall. Meanwhile, Ted & Barney offer to keep watch over the bar at MacLaren's while awaiting their dates, since Carl wants to close up early.

Hallie loses her parent's trust when she sneaks out of the house to a college party. Rita is not sure how to respond to Patty's request to let her personal trainer join the band, and Rita and Jay are convinced by Shannon to host a birthday party for their dog.

Jack and Tony use creative means to force Matobo out of his saferoom and prepare to leave with their captor when Agent Walker arrives on the scene, prompting Emerson to make some quick decisions. Agents Moss and Gold are sidetracked from their mission to find Walker when a representative from the Attorney General's office arrives to question them regarding the interrogation of Tanner. Henry receives new information about the death of his son when he follows a lead from Samantha Roth.

Lucas and Julian have a difficult time finding the right director for their movie. Meanwhile, a present from Lucas confuses Peyton and Brooke battles with romantic complications.

When Alan finds out that Judith is pregnant, he assumes that he is the father. Charlie is convinced he knows the reason behind Jake's bad mood.

Erica is sent back to her first sexual experience to get to the roots of her relationship troubles.

When Sam sees a litter of puppies being born, he worries he might not be able to handle the birth of his own child.

Horatio finds out that Ryan has a connection to the case when a murder occurs during a horse race.

Jay and Adam's "guys night out" leads to major scandal when Samantha reveals that Adam wasn't exactly faithful to his girlfriend.

Bear wraps up warm as he heads to the fozen wastelands of North US. He goes underground to search an abandoned mine, and he takes to some fast moving water...as usual.

Anthony takes a look at all that Washington, DC has to offer.

Washington, D.C. Bureau Chief for Al Jazeera Abderrahim Foukara

Tonight Stephen welcomes New York Times columnist Frank Rich.

After Kenpachi defeats Nnoitra, he demands Orihime heal him. Before Orihime reaches him, the Espada Stark arrives and takes her away to a tower where S... suke Aizen greets her. He informs her that he, Gin Ichimaru, and Kaname T... sen are preparing to destroy Karakura Town. Aizen orders T... sen to contact all of the Soul Reaper captains, Ichigo, and his friends with kid?, and reveals that he brought Orihime to Hueco Mundo to lure and trap them. As he travels through a garganta portal to Karakura Town, however, Aizen is confronted by Commander-General Shigekuni Yamamoto-Genry... sai, the leader of the Gotei 13, with five other captains. Aizen summons the Espada Stark, Barragan, and Halibel and orders Espada Ulquiorra Schiffer to protect Las Noches.

Joseph worries that Jac may be pregnant when she complains of feeling sick. Ric battles to save the lives of a security guard and the drug addict who stabbed her while at the same time trying to placate the victim's fiance and the Press. After confessing to his priest about his feelings for an engaged woman, Linden learns Callie knows the truth about the night of the accident