Stardate: 50384.2 The crew of Voyager watches a once in a lifetime event of a supernova. With the conclusion of the explosion, a tired Janeway returns to her quarters to find Q waiting for her with a request to have a child with him. Janeway refuses, but Q will not go away. Fortunately, the matter of a Q-human child is put on hold when Q's significant other arrives on the scene. Moments later, several more supernovae are witnessed.

During an argument with Donna in the student union, David throws a tantrum and cuts his hand on a glass. He must see a psychiatrist after displaying hostile behavior toward the ER staff. Mel agrees with the doctor's recommendation that David be held 72 hours for observation. David is diagnosed with a mild form of manic depression. His mother comes to see him and advises him to moderate his behavior; he will not require medication if he seeks therapy and stops drinking. David thanks Donna for her support, and they decide to get back together. Steve faces plagiarism charges; Professor Randall, who assumed control of the independent study course after returning to C.U., recognized Brandon's writing. Randall still holds a vendetta against Brandon, and brings collusion charges against him. Kelly's and Mark's plans for a romantic weekend getaway are foiled by a lost reservation. They finally secure a motel room, only to come down with food poisoning. The gang helps Willie build a house, which his family will receive from Habitat for Humanity. Val displays construction skills as a result of working with her contractor father, but hints to Clare that she has few happy memories of her dad. Everyone eats Thanksgiving dinner inside the unfinished house.

With only days left before the deadline to start a business, Flora decides to pursue a coffee shop concept in addition to the dessert delivery service. She and partner Mark frantically try to get the necessary materials together, but Flora's power plays alienate the roommates. In the end, the investors decide that their conditions have not been met. There will be no business. In the midst of all this, Dan finds out that he'll be moving to Milan to model, and has to break the news to his boyfriend Johnny.

With the Vorlons destroying whole worlds, Babylon 5 is struggling to cope with the refugees. And with one Vorlon aboard, they cannot make a move without them knowing about it. So Sheridan decides to kill him. On Centauri Prime, Cartagia explains to Londo how he will become a god when the Vorlons destroy the planet.