Bailey teams with Seattle Grace's new pediatric surgeon, Dr. Arizona Robbins, to save the life of a young patient near and dear to her heart, as the admittance of a death row inmate at the hospital stirs anger in Derek and further erodes Meredith and Cristina's friendship; meanwhile, Callie and Sloan work as a team to fight their respective attractions to Sadie and Lexie, and Izzie tells Alex that she's seeing Denny.

A young Earl gets his heart broken by the babysitter and swears revenge on her and her boyfriend. Now, Earl is older and wiser, so he decides to cross them off his list, but it may have terrible repercussions for Randy. Meanwhile, Joy loses Darnell's pet turtle.

Betty finds it hard to impress her idol, Jodie Papadakis who is an editor at YETI, while making a mess of her work and family life. Betty's has a disastrous encounter with the assistant at ELLE magazine.

Kim decides to pursue a career as a news anchor for a local TV station. Craig has a mishap with Phil's car, which only gets worse when the police get involved.

A measles outbreak forces Oceanside into quarantine lockdown, while Naomi pressures Addison into helping her Pacific Wellcare rival, Wyatt, on a case.

Jenna thinks Liz is only attracted to a guy because she wants a child, while Jack helps Tracy and his wife Angie develop a "post-nup" and helps get Jenna an audition to play Janis Joplin.

When a drug deal goes bad, two brothers sustain serious injuries and are brought to the ER. Tensions continue between Gates and Sam, coming to a head when Tony is the last to know Alex is about to be released from the hospital. Neela has to tell a young girl with sickle cell anemia that she must have an operation, and the case leads her to consider specializing in pediatric surgery. Banfield ponders her choices about expanding her family.

Guest: White House Press Secretary Dana Perino

Tonight Stephen welcomes Wired columnist and author of Remix: Making Art and Commerce Thrive in the Hybrid Economy, Lawrence Lessig.

A Flotsam episode with Stephen Fry and Alan Davies, as well as guests Rob Brydon, Andy Hamilton and Charlie Higson.