On a world where a biological weapon wiped out most of the male population, Quinn, Rembrandt and Arturo become objects of desire and are imprisoned by the government to be breeders. As they try to escape and regroup with Wade, they find there are others out to capture them.

An ancient artifact, which was brought to Boston from an excavation site in South America, is believed to be linked to a series of deaths. While Scully suspects that political terrorism may be behind the murders, Mulder believes in something far more sinister.