The trail of a mysterious organization called the "Army of the 12 Monkeys" leads Cole to a mental institution in 2015, where a patient holds the key to the plague that destroys the world. Meanwhile, despite warnings that her involvement may disrupt the course of history, Dr. Railly risks her life to help him.
Utilizing a dangerous and untested method of time travel, James Cole journeys from 2043 to the present day on a mission to locate and eradicate the source of a deadly plague that will all but annihilate the human race.
Cole is a convicted criminal in a post-apocalyptic future where the Earth's population is forced to live underground after a deadly virus. In a bid to earn a pardon, Cole uses the imperfect science of time travel to help collect information on the virus released by the Army of the Twelve Monkeys.
12 Monkeys - Mentally Divergent Synopsis and Schedule