Annie continues to suffer through her mother's recent leukemia diagnosis. Annie then decides to go to Arizona to visit them and see what is going on with them. Meanwhile, Eric volunteers for a charity work, but he's unable to do it at the last minute. Matt then volunteers to do it, but his dating habits get him into trouble with the organization he is doing charity for. Also, Mary decides to call it a quits with Jeff while Lucy has her first real date with her classmate Jimmy Moon. Lastly, when Annie returns home with her parents, they decide to stay with her and the rest of the family so that they could spend some more time with them - which unfortunately will be the last for Annie's mom, Jenny.
Reverend Eric Camden and his wife Annie have always had their hands full caring for seven children, not to mention the friends, sweethearts and spouses that continually come and go in the Camden household. This year, Eric and Annie will find their family back together in Glenoak with the return of Matt and Simon.
As is often the case when the house is overflowing with Camdens, Eric and Annie are in for a bumpy ride as their children take landmark steps in their lives. Meanwhile, Eric and Annie continue their journey as soul mates, parents and grandparents whose love and respect for each other brings them ever closer.
Through all the ups and downs, Eric and Annie have managed to keep their romance alive and their family together. Not only are they raising their own seven children, they've picked up several additional family members along the way.