Annie decides to take a much-needed break from the family and heads to the beach on a solo trip to get some rest, leaving Eric (Mr. Mom) in charge of the large household. Meanwhile, Matt must relunctantly say goodbye to Shana as she leaves for NYU. Mary impatiently waits for Robbie to call her. Also, Lucy realizes that she may be interested in the wrong guy, and Simon learns some tips from his sisters on how to treat a girl.
Reverend Eric Camden and his wife Annie have always had their hands full caring for seven children, not to mention the friends, sweethearts and spouses that continually come and go in the Camden household. This year, Eric and Annie will find their family back together in Glenoak with the return of Matt and Simon.
As is often the case when the house is overflowing with Camdens, Eric and Annie are in for a bumpy ride as their children take landmark steps in their lives. Meanwhile, Eric and Annie continue their journey as soul mates, parents and grandparents whose love and respect for each other brings them ever closer.
Through all the ups and downs, Eric and Annie have managed to keep their romance alive and their family together. Not only are they raising their own seven children, they've picked up several additional family members along the way.