The Glenoak Community is making a big fuss over a petition that is protesting the apparently unfair firing of one of Ruthie's teachers, Mrs. Miller at her private school. Although, Matt knows the real reason of why she is leaving since she has been to his hospital after being diagnosed with advanced breast cancer, which leads to the embarrassment of many of the petitioners - including Simon and Lucy when they encounter her brother who's a teacher at their high school. Also, Annie's father Charles drops by at the Camden's for a visit. Annie is then surprised and shocked when her father passes on news to Eric - to tell her that she has a sister, Lily.
Reverend Eric Camden and his wife Annie have always had their hands full caring for seven children, not to mention the friends, sweethearts and spouses that continually come and go in the Camden household. This year, Eric and Annie will find their family back together in Glenoak with the return of Matt and Simon.
As is often the case when the house is overflowing with Camdens, Eric and Annie are in for a bumpy ride as their children take landmark steps in their lives. Meanwhile, Eric and Annie continue their journey as soul mates, parents and grandparents whose love and respect for each other brings them ever closer.
Through all the ups and downs, Eric and Annie have managed to keep their romance alive and their family together. Not only are they raising their own seven children, they've picked up several additional family members along the way.