With Annie out of town, Eric is left alone to accompany Simon on his visit to the Board of Education to discuss early graduation. During the meeting, Simon bonds with his advisor, Maynard (guest-star Cirroc Lofton), when they realize that they're both preachers' kids. Meanwhile, Lucy catches Chandler kissing a beautiful blonde woman at church and she agonizes over whether or not to tell Roxanne; Kevin's (George Stults) boss, Detective Michaels (guest-star Christopher Michael), tricks him into babysitting his six-year-old granddaughter; Peter makes a deal with the school bully in an attempt to protect Ruthie and Cecilia agrees to watch the twins which leads to a confrontation with Simon.
Reverend Eric Camden and his wife Annie have always had their hands full caring for seven children, not to mention the friends, sweethearts and spouses that continually come and go in the Camden household. This year, Eric and Annie will find their family back together in Glenoak with the return of Matt and Simon.
As is often the case when the house is overflowing with Camdens, Eric and Annie are in for a bumpy ride as their children take landmark steps in their lives. Meanwhile, Eric and Annie continue their journey as soul mates, parents and grandparents whose love and respect for each other brings them ever closer.
Through all the ups and downs, Eric and Annie have managed to keep their romance alive and their family together. Not only are they raising their own seven children, they've picked up several additional family members along the way.