After discovering that Mary (Jessica Biel, who does not appear in the episode) has filed for divorce and signed away custody of her son, Matt is at a loss for how he should to break the awful news to Eric and Annie. Simon informs his new girlfriend, Rose (guest-star Sarah Thompson), that he won't have sex with her, but avoids telling her the reason behind his decision. She gets fed up with him but comes back to him when she finds out his true intentions for them - marriage. Meanwhile, Ruthie's boyfriend, Vincent (guest-star Thomas Dekker), asks Martin to get Ruthie to break up with him. Also, Eric gets involved once again with the Davis family children when little boy Danny (guest-star Drake Johnston) is being adopted by Cecilia's parents, George and Gwen (guest-star Brad Maule and Holly Fulger), but forgets to mention that the kid is part of a package deal as Danny has three sisters in Social Services as well, and try to take them in as well. Kevin is about fed up with Lucy as he's frustrated that they haven't moved out of the Camden home as Lucy is stalling with the Realtor over a new home. Lastly, Lucy and Kevin may have finally found the perfect house.
Reverend Eric Camden and his wife Annie have always had their hands full caring for seven children, not to mention the friends, sweethearts and spouses that continually come and go in the Camden household. This year, Eric and Annie will find their family back together in Glenoak with the return of Matt and Simon.
As is often the case when the house is overflowing with Camdens, Eric and Annie are in for a bumpy ride as their children take landmark steps in their lives. Meanwhile, Eric and Annie continue their journey as soul mates, parents and grandparents whose love and respect for each other brings them ever closer.
Through all the ups and downs, Eric and Annie have managed to keep their romance alive and their family together. Not only are they raising their own seven children, they've picked up several additional family members along the way.