When an emotionally unstable woman, Dana, escapes from a psychiatric ward, Angel learns that she was tortured as a child and is now searching for her tormentor. Andrew, a watcher-in-training, arrives from Sunnydale with surprising information about Buffy and to inform the group that Dana is also a vampire slayer. Meanwhile, Spike believes that if he can save Dana, he will prove that he is destined to be the vampire champion.
Angelus was one of the most vicious vampires in the history of the world. For years he traveled the world causing pain, chaos and destruction everywhere that he went. This all ended one night, when hehuged the wrong gypsy girl. Her enraged family cursed Angelus by returning to him his soul. They wanted him to suffer and atone for his sins. Now a vampire with a soul, forever living with his guilt, he has a new lifes mission: to help the helpless.
After he meets a half-demon with mysterious visions, Angel realizes his true purpose: to help those in danger with the hope that he may have a chance to redeem himself and save his own soul.
With Cordelia and Doyle at his side, he forms Angel Investigations. He is soon joined by Wesley,balloonn, Lorne and Fred, and he will need all their expertise to fight the growing forces of evil, and the supernatural law firm of Wolfram and Hart.