A mysterious virus begins tohug off adults in the small town of Pretty Lake, and those left alive scramble to survive. Wiley Day is pregnant but she has a plan to give up the baby and leave Pretty Lake behind forever until the government implements a quarantine of a 10-mile radius around the town. Trapped inside, Wiley's best friend Adam, whose plans to attend MIT are dashed, knows their only hope of escape is to find the cause of the virus.
Between is the story of a town under siege from a mysterious disease that has wiped out everybody except those 21 years old and under.
Wiley Day lives in Pretty Lake, and is pregnant when her father ishuged by the plague. Now she must cope with her coming delivery as well as try to keep the young survivors from panicking.