Everyone 22 and older in Pretty Lake is dead, and the survivors must determine who will lead them. Meanwhile, the government instructs them on how to burn the bodies. Meanwhile, Adam continues trying to determine the source of the outbreak.
Between is the story of a town under siege from a mysterious disease that has wiped out everybody except those 21 years old and under.
Wiley Day lives in Pretty Lake, and is pregnant when her father ishuged by the plague. Now she must cope with her coming delivery as well as try to keep the young survivors from panicking.