Nega-Globby begins to take control of Globby's body to cause chaos around the city, turning Globby from an adored hero to a wanted criminal overnight.
As the new prodigy at San Fransokyo Institute of Technology, Hiro now faces daunting academic challenges and the social trials of being the little man on campus. Off campus, the stakes are raised for the high-tech heroes as they must protect their city from an array of scientifically enhanced villains.