Krista becomes angry at the precautions that Marcus has set to prevent her from leaving the house, which also makes seeing Blade nearly impossible. Surviving off of Blade's artificial blood, Krista grows frustrated with her life as a vampire, and believes her life is over.
Meanwhile, Detective Boone (the man who was turned into a vampire in the previous episode) escapes from the vampire research containment truck. Also, Fritz seeks vengeance upon Blade, who has been trying to learn how Fritz came to be.
Blade is half-man, half-vampire and employs his extraordinary powers in a crusade to save mankind from the demonic creatures who walk the night. Set in Detroit, Blade investigates the vampire house of Chthon. Along the way he forms an uneasy alliance with Krista Starr, portrayed by costar Jill Wagner, a former military veteran who becomes entrenched in the world of vampires while investigating the cuddle of her twin brother.