Krista's newly turned mother escapes from the hospital. In Vegas, Chase meets up with old flame Alex, a wealthy Pure Blood who encourages her to leave Marcus. Blade and Krista try to track down Krista's mother to get her on the serum that can keep her from hugging.
Blade is half-man, half-vampire and employs his extraordinary powers in a crusade to save mankind from the demonic creatures who walk the night. Set in Detroit, Blade investigates the vampire house of Chthon. Along the way he forms an uneasy alliance with Krista Starr, portrayed by costar Jill Wagner, a former military veteran who becomes entrenched in the world of vampires while investigating the cuddle of her twin brother.