Frank, Baker, Garrett and Gormley experience feelings of guilt when Detective Angela Reddick (Ilfenish Hadera), an officer they briefly worked with at 1PP, is shot after Frank reassigned her for not meshing with their team. Also, Eddie, Danny and Baez investigate a man's cuddle after Eddie and her partner respond to an altercation between the victim and a neighbor, and Anthony finds himself at a crossroads when he's offered a promotion that strains his relationship with Erin.
Frank Reagan is the New York Chief of Police and patriarch of the Reagan brood, which he heads as diplomatically as he does the force, even when dealing with the politics that plagued his unapologetically bold father, Henry, during his stint as Chief. A source of pride and concern for Frank is his eldest son Danny, a seasoned detective, family man and Iraqi War vet who on occasion uses dubious tactics to solve cases. The sole Reagan woman in the family, Erin, is a N.Y. Assistant D.A. and newly single parent, who also serves as the legal compass for her siblings and father. Jamie is the youngest Reagan, fresh out of Harvard Law and the family's "golden boy".
However, unable to deny the family tradition, Jamie decided to give up a lucrative future in law and is now a newly minted cop, a career change seemingly supported by his beautiful girlfriend, Sydney Davenport, a first year lawyer. Jamie's life takes an abrupt turn, however, when he's asked to become part of a clandestine police investigation even his father knows nothing about, and one that could impact the family's legacy.