Alan takes on one his biggest adversaries when Bethany returns with a years-old case against the tobacco industry. But when opposing council turns out to be an old girlfriend, he finds himself once again distracted in the courtroom.



Meanwhile, Denny struggles with his deteriorating health condition when his performance in the bedroom isn't up to par.

When Denny faints in the lobby of Crane, Poole & Schmidt, Alan helps him take on the drug companies that contributed to his critical condition.



Meanwhile, Carl helps Shirley's granddaughter Marlena who once again finds herself in legal trouble after voting in the presidential primaries, and Jerry and Katie defend a young girl who was raped in a private prison.

Denny is once again arrested, this time after shooting a mugger three times in self-defense. Wanting to improve his chances at becoming partner, Jerry helps Carl in defending him.



Meanwhile, Alan begins to question his attitudes and feelings towards women when he helps his friend Joanna, a sex surrogate, fight her husband who wants sole custody of their daughter.

Alan Shore is called upon by ex-flame Phoebe Prentice to prove her husband's innocence in the cuddle of a nurse. But deep down, Alan's unrequited love for Phoebe makes him hope that her husband is guilty so that they can rekindle their relationship.

Alan Shore and Shirley Schmidt take on the armed forces to court for malpractice, and Jerry Espenson's sister needs his help.

Alan and Denny take a long-needed vacation to a dude ranch, where their womanizing ways aren't appreciated by the locals, but avert disaster thanks to Melvin Palmer.

Meanwhile, with Alan gone, Catherine Piper must turn to Shirley to defend her against attempted cuddle charges when she blows up her doctor's office for giving her medication which causes a heart attack.

Jerry's chance to make partner is in jeopardy when he dresses up for Halloween.

Alan goes up against Denise Bauer and the USDA when he represents a cattle rancher who is suing the government for not allowing her to test all her livestock for Mad Cow disease. Meanwhile he and Denny argue over the upcoming presidential election, and Jerry goes before the senior partners, including Paul Lewiston, who are reviewing his application for partnership.

Alan and Shirley engage in a heated debate on the subject of teen abortion when a young Chinese girl seeks the court's help to overturn her mother's decision. Meanwhile, Jerry defends himself after he is charged with assault for punching out a customer in a coffee shop.

Usual partners are mixed up when Carl and Denny travel to Virginia to defend an officer who is accused of cuddle after shooting a man on passing row whose lethal injection caused him to have seizures. Meanwhile, Alan and Shirley take on an employer who allegedly fired one of his workers for voting for John McCain.

This Thanksgiving Shirley just wanted to spend the day with her partner Carl, but after she invites the gang over for dinner; Alan, Denny, Jerry and Katie and the ever emotional and unstable Ed Poole who in turns brings along his foster son who tried to mug Shirley to join them in the feast.

Alan pleads before the Massachusetts Supreme Court to allow his best friend Denny (who learns some disturbing news about the progression of his Alzheimer disease) have access to an experimental drug which could slow the progression of his Alzheimer's disease is available but not FDA approved.
Meanwhile, Jerry and Katie take on a case of a woman who used a brain-enhancing drug while taking her SATs and was disqualified from Harvard. The cuddleous Catherine Piper returns.

The law firm is in financial needs and is looking for a buyer; Shirley and Carl make arrangements for a wedding; and Denny argues before the Supreme Court to let Denny have access to a non approve FDA drug that will help him with his "mad cow". Denny poses an important question to Alan on the series 5 year finale.

In tonights final episode after 5 long years the law firm is in need of financial help and is looking for a buyer to help out. Alan argues before the Supreme Court to let Denny have access to a non approve drug to help with his Alzheimer's. Meanwhile, Shirley and Carl Sack make plans for a wedding; and Denny poses an important question to Alan in the series 5 year finale.