Eliminating Gus does nothing to calm Skyler's fear for her family's safety. In fact, she now fears her own husband most of all. With Walt, Jesse, and eventually Mike now on the same page, the three set out to get rid of any remaining evidence of Gus' operation. Also, Ted awakens from his coma.

Walt and Jesse want to get their meth business booming again, but to do that they need help. They approach Mike with hopes that he'll become a partner, only to be flatly rebuffed. Meanwhile, a former business associate of Gus Fring's becomes paranoid of being tied to the DEA's ongoing investigation, and resorts to drastic measures to protect herself.

Walt, Jessie, and Mike's business starts back up. Walt finds an ingenious solution to the problem of where to set up the lab, Jesse makes a decision about his personal life, and Mike visits each of his crew to ensure that they stay mum, even with the feds pressuring them. Hank goes back to work. Skyler remains numb, and Marie badgers her about what's wrong. Walt is in for a surprise when Mike divides the money from the first cook.

Walt celebrates his fifty-first birthday, and decides to do so in style. He buys himself and Walt Jr. new sports cars, and generally flaunts his wealth. Walt's new associate Lydia freaks out when the DEA searches the offices of Madrigal. Skyler insists the children stay with Hank and Marie. Hank is offered a promotion to ASAC.

Walt uses covert tactics to place a bug in Hank's office, with plans to monitor the ongoing DEA investigation into Madrigal. The business is also in need of a large quantity of methylamine in order to cook. Lydia proposes a novel idea: get the chemical via a good old fashioned train robbery. Also, Walt Jr. grows increasingly sick of staying with his aunt and uncle.

Walt, Jesse and Mike distress over the future of their business; occupational hazards weigh heavily on Jesse.

Walt, Jesse, and Mike meet with a Phoenix based meth dealer named Declan. The group hashes out a new distribution deal, but Jesse and Mike still want out. Mike leaves, but Walt refuses to pay Jesse what he's owed. Meanwhile, Hank closes in on Mike, leading Walt to warn him and suggest he skip town. Sadly, Walt and Mike's final meeting doesn't at all go according to plan.

With one less variable in the equation, Walt sets out to tie up any remaining loose ends. He strikes a deal with Lydia to expand his reach to the Czech Republic, and puts a hit out on all of Mike's remaining associates. Business is booming again, but Skyler decides to make one last ditch effort to save her family. Also, Hank comes to a shocking realization about 'Heisenberg'.

Still reeling from his realization that Walt is Heisenberg, Hank suffers a panic attack while driving home. While he recuperates, Hank demands that all the materials on the Gus Fring case be brought to his house for review. Jesse has trouble facing all that he's done, and worries that Walt has had Mikehuged. Walt's cancer comes back, and he returns to chemo. He also discovers a tracking device on his car, leading to an explosive confrontation with Hank.

Following Walt's heated confrontation with Hank, he leaves and attempts to call Skyler. To his horror, she's already on the phone with Hank. Hank begs Skyler to give a statement about Walt's activities, but she realizes he has no proof, and clams up. Meanwhile, Walt buries his money in the desert, and Lydia takes drastic measures to alter her business relationship with Declan. Also, a distraught Jesse gets himself arrested, opening a new door for Hank.

Alone with Jesse in the interrogation room, Hank tries to get him to flip on Walt. Jesse refuses, and Saul gets him released. Elsewhere, Marie tries to lure Jr. over to her home, causing Walt to hold a public meeting involving he, Hank, Marie, and Skyler. Hank refuses to give up the chase, leading Walt to unleash a bombshell of epic proportions. Finally, Walt talks Jesse into leaving town, but a shocking revelation throws a wrench into the plan.

Walt returns home to find that Jesse decided not to burn the place down. Unbeknownst to Heisenberg, Jesse's plan was actually thwarted by Hank's intervention. Jesse agrees to help bring down Walt, while an unassuming Mr. White tries to mend fences. Skyler urges her husband to take drastic action, but Walt won't listen. Walt then prepares to meet with Jesse, unaware that the DEA is ready and waiting to pounce.

Things heat up for Walter White in unexpected ways.

Everyone copes with radically changed circumstances.

Events set in motion long ago move toward a conclusion.

All bad things must come to an end.