Grissom and his crew handle their highest profile case to date when the city's former chief of detectives is slain execution-style in his house following a wild party. Missing from the residence are the chief's trophy wife and their 7-year-old daughter. When several motorists report seeing the girl along an access road near Miami, Catherine and Warrick fly there and meet that city's top CSI, Horatio Caine, who aids them in the investigation.
Season 2 Episode 22 of CSI resulted in a 0.00 rating in the 18-49 demographic.
In the city of Las Vegas, Nevada, its reputation for providing instant success for those willing to try their luck draws in the hopeful and the naive. This constant influx of visitors also provides ripe targets for criminals of all varieties, confident they will never be caught. Unfortunately for them, most are proven wrong by the Las Vegas Police Department's night shift Crime Scene Investigations unit led by ex-stripper and single parent Catherine Willows.
With almost obsessive dedication towards her quest for the facts, she and her elite team of investigators work various perplexing cases using scientific skills and equipment that are capable of finding valuable clues from the most seemingly unlikely sources.
Her team includes second-in-command Nick Stokes, who was Texas-born and -bred; Sara Sidle, who recently returned from a leave of absence; Greg Sanders, a former DNA Tech, and Morgan Brody, daughter of the under-sheriff and new transfer from Los Angeles, California. Assisting them are Jim Brass, an experienced LVPD Captain; Al Robbins and David Phillips, the Chief ME and his assistant; and David Hodges, a trace technician who hates field work.