As an excited Portwenn digests the news that Martin and Louisa are engaged, it's business as usual for the doctor. Beth Sawle's knee wound is not responding to the treatment he's prescribed, and when Martin visits the remote cottage where she lives with her strange sister Janet, he makes a disturbing discovery. Meanwhile, Bert's restaurant is in financial trouble, prompting son Al to take decisive action.
Make an appointment with the brilliant but socially awkward and neurotic Doc Martin. When Martin develops an aversion to blood, he abandons his career as a celebrated London surgeon and becomes the only doctor in a sleepy small town where his tactless manner soon has the whole town in an uproar.