Webby, who has been feeling overlooked, ends up becoming a giantess after falling into a mysterious pool in the jungle. While she is now the center of attention, she does not like it very much. While Scrooge searches for a way to reverse the process, a corrupt circus owner seeks to kidnap Webby for his new sideshow.
When Donald Duck decides to join the Navy, he leaves his nephews, Huey, Dewey and Louie, in the care of his cantankerous Uncle Scrooge. He is an eccentric and miserly billionare who loves to literally swim in his money that is held in his corporate headquarters/vault known as the Money Bin. While the initial meeting was less than pleasant, events soon have them, along with a newly hired nanny, her daughter and Scrooge's stupid but skilled pilot, on countless adventures as the group goes around the world looking for treasure, or defending Scrooge's current assets from enemies like the Beagle Boys or Magica De Spell.