A car accident leads U.S. Marshal Jack Carter into the unique Pacific Northwest town of Eureka.
After a strange accident sidelines Eureka's sheriff, Jack Carter takes over the investigation into the mysterious phenomenon that led to the passing of a resident.
Carter learns about the secret purpose of the town while trying to re-establish a connection with his angry and bitter daughter, Zoe. He develops a friendly working relationship with government liaison Allison Blake and meets some of the more eccentric residents of Eureka.
Carter and the other citizens of Eureka attend the funeral of Susan and Walter Perkins. Much to their surprise, Susan makes a return to Eureka as a woman who is very much alive!
Jack Carter accidentally shoots Henry while suffering from short-term memory loss. A visit from a noted scientist may hold clues into Carter's sudden memory loss.
Spencer is apparently abducted by aliens and then returned to Earth the next day inside a crop circle. Also, the town is visited by Congressman Arnold Faraday, whose committee is responsible for Eureka's government funding.
After a lab accident, Global Dynamics researcher Carl Carlson is expelled from Eureka due to lack of results. Later, it is discovered that the accident has unlocked hidden abilities in Carl. Meanwhile, Jack does his best to avoid a physical.
After Fargo and Spencer accidentally activate a doomsday device, Carter must help Dr. Irwin Thatcher, an aging scientist, to shut down the machine.
Carter investigates an unusual car accident. Meanwhile, Stark is under stress to produce results on a project.
When the return of Eureka's star pupil causes problems all over town, Stark is forced to make a hard choice. Carter attempts to track down Zoe who has run off with the former resident.
A nanotech experiment escapes from Global Dynamics. The project, which bridges the gap between computers and human brains, threatens to overrun Eureka when it begins duplicating Stark.
Sheriff Carter and Zoe are the only ones unaffected when Eureka's residents begin to behave strangely. The father and daughter team search for the cause.
S.A.R.A.H. the artificial intelligence that runs Carter's house takes him and a group of residents hostage in an intervention to keep Carter in Eureka. Meanwhile, S.A.R.A.H.'s root program B.R.A.D. activates and turns the situation deadly.
Following an experiment on the artifact, Eureka warps to 2010. However, temporal anomalies begin to cause problems for Eureka, which leads to a shocking revelation.