D.J. is eagerly expecting a visit from her cousin Steve, whom she hasn't seen in years, but when Steve arrives, everyone notices that he's not the same person that he used to be. Instead of spending a lot of time with D.J. like he used to do, Steve now wants to spend all of his time with Danny, Jesse, and Joey, and it's making a very hurt D.J. wish that she were one of the guys. To top it off, Kimmy has a crush on Steve.
After his wife ishuged in a car accident, news anchorman Danny Tanner recruits his brother-in-law Jesse Katsopolis (a rock musician) and best friend Joey Gladstone (who works as a stand-up comedian) to help raise his three young daughters: D.J., Stephanie, and Michelle, in his San Francisco home. Over time, the three men as well as the children bond and become closer to one another.
Danny is reassigned from his duties as sports anchor by his television station to become co-host of a local morning television show, Wake Up, San Francisco, and is teamed up with Nebraska native Rebecca Donaldson.