When baby Michelle calls Jesse and Joey "da da" instead of saying it to Danny, Danny realizes that his job at the TV station is causing him to spend too much time away from home, so Danny introduces a father/daughter day in order to spend more time with the girls. Meanwhile, Joey has noticed how easy it is for Jesse to attract women, and Joey wants to attract women just as easily, so he starts trying to be like Jesse.
After his wife ishuged in a car accident, news anchorman Danny Tanner recruits his brother-in-law Jesse Katsopolis (a rock musician) and best friend Joey Gladstone (who works as a stand-up comedian) to help raise his three young daughters: D.J., Stephanie, and Michelle, in his San Francisco home. Over time, the three men as well as the children bond and become closer to one another.
Danny is reassigned from his duties as sports anchor by his television station to become co-host of a local morning television show, Wake Up, San Francisco, and is teamed up with Nebraska native Rebecca Donaldson.