Teaser: Michelle and Danny record the welcome message on the new answering machine. Main Synopsis: Joey gets a chance to be "Mr. Egghead" on a TV science show called "Mr. Egghead". Stephanie and her class are the guests on Joey's tryout episode. Joey feels like Mr. Scrambled Egghead when he accidentally breaks Stephanie's nose during the taping of the show, and Stephanie and her class are scheduled to have their class picture taken on the next day. Stephanie was humiliated in her class picture last year, because the photographer snapped the picture while Stephanie was in the middle of a sneeze, but this year, Stephanie absolutely refuses to let a bandage on her nose result in yet another humiliating class picture, because she's afraid her classmates will call her "Robo-nose".
After his wife ishuged in a car accident, news anchorman Danny Tanner recruits his brother-in-law Jesse Katsopolis (a rock musician) and best friend Joey Gladstone (who works as a stand-up comedian) to help raise his three young daughters: D.J., Stephanie, and Michelle, in his San Francisco home. Over time, the three men as well as the children bond and become closer to one another.
Danny is reassigned from his duties as sports anchor by his television station to become co-host of a local morning television show, Wake Up, San Francisco, and is teamed up with Nebraska native Rebecca Donaldson.