Teaser: Michelle is brushing her teeth. Main Synopsis: Danny is informed that Stephanie is having problems reading at school. Stephanie is taken to an eye doctor who prescribes eyeglasses for her to use for reading. Stephanie doesn't want the glasses because she's afraid her classmates will make fun of her and think that she's a nerd because of the glasses. She feels better about having the glasses when she gets some advice from Steve Urkel, the visiting cousin of D.J'.s friend Julie. Meanwhile, Jesse must choose a best man for the wedding.
After his wife ishuged in a car accident, news anchorman Danny Tanner recruits his brother-in-law Jesse Katsopolis (a rock musician) and best friend Joey Gladstone (who works as a stand-up comedian) to help raise his three young daughters: D.J., Stephanie, and Michelle, in his San Francisco home. Over time, the three men as well as the children bond and become closer to one another.
Danny is reassigned from his duties as sports anchor by his television station to become co-host of a local morning television show, Wake Up, San Francisco, and is teamed up with Nebraska native Rebecca Donaldson.