Zoe Hart finds a roadblock in her long term plan when she's told if she wants to get any further she'll have to work on her people skills. This leads her to do something that she'd been avoiding and she leaves Manhattan for Bluebell, Alabama to become the new local General Practitioner.
Hoping it might help the residents of Bluebell accept her as one of their own, Zoe accepts an invitation to join Mayor Hayes on his float in the Founder's Day Parade. However, Zoe accidentally crashes his float, hurting her chances of winning over Lemon and the Bluebell residents.
Zoe is determined to win Bluebell's gumbo contest and prove to everyone that she is a part of the community, which will hopefully help her land some patients.
As Bluebell is hit by an intense heat wave, Zoe discovers that the hot weather makes everyone act differently and with a lot less inhibition In fact, it takes all of Zoe's strength to ignore her heat-induced attraction to Wade until it gets the best of her.
Zoe discovers something shocking about the local minister and his wife, causing quite a stir among the residents of Bluebell.
Driving home late one night from a house call, Zoe accidentally hits a man but can't find any signs of him when she gets out of her car. Later, she sees the man's photo hanging in the Rammer Jammer, and George has to break the news to her that the man in the picture died over a year ago.
When Nascar\'s Brian Vickers has to drop out of hosting Bluebell Junior League\'s annual turtle race, Lemon is reluctantly convinced that the mayor is the perfect replacement as her co-host. Zoe is asked out on a date by a handsome local veterinarian, Dr. Judson Lyons.
Noticing that Zoe is feeling homesick, Lavon suggests that she host his annual pre-game homecoming party to help her feel more connected to Bluebell. Zoe jumps at the opportunity and decides to enlist the help of her friend Gigi from New York, but as it turns out New York and Bluebell have very different ideas of what makes a good party.
While the residents of Bluebell prepare for their annual Planksgiving celebration, Zoe anxiously counts the days until her return home to New York for Thanksgiving.
Zoe encourages Rose to enter the annual Miss Cinnamon Cider Pageant even though Lemon\'s younger sister, Magnolia Breeland, is a shoo-in to win. Of course, with Zoe coaching Rose and Lemon coaching Magnolia, rivalry takes on a whole new meaning.
When Zoe goes in search of some family history in Bluebell, she discovers that she is a legacy to the Bluebell Belles. Of course, once Lemon catches wind of the news, she makes it her sole mission in life to make sure Zoe doesn't become an official Belle and puts her through a humiliating initiation.
Zoe is so uncharacteristically happy as of late that it causes her friends to speculate as to the possible reason behind her new attitude. Turns out that Zoe is hiding her new friendship with AnnaBeth, who doesn\'t want Lemon to find out since Zoe is Lemon\'s sworn enemy.
Zoe decides that it\'s too soon in her relationship with Judson to go to the annual Sweetie Pie Dance so instead she makes plans to have a sleepover with Rose, whose parents are going out of town. George misplaces the save the dates for his upcoming wedding which causes major trouble in Lemon paradise.
Wade somehow convinces Lemon to dress up as Joelle as part of a scheme to convince Joelle\'s ex-boyfriend that he didn\'t actually see Wade and Joelle together. Lavon asks Zoe to help him figure out why Didi has been avoiding him, but once Zoe uncovers the shocking reason she isn\'t quite sure what to do with the information. George comes to Zoe for advice in determining whether there is a medical explanation for the behavior of one of his clients.
Zoe Hart is thrilled to see snow in Bluebell, but the rest of the town is superstitious that it will bring bad luck. When Lavon\'s parents make a visit to Bluebell, Lavon thinks it\'s the perfect opportunity to introduce them to Didi, but the introduction doesn\'t exactly go according to plan. Lemon and George make a big decision about their future.
Much to Brick\'s disappointment, George is named Bluebell\'s Man of the Year. As the town\'s mayor, Lavon is expected to host a cocktail party in George\'s honor, but for obvious reasons this is a difficult situation for Lavon given his history with Lemon. Fortunately for Lavon, Zoe agrees to step in and help him with the party, but things take a turn for the disastrous when Zoe has to improvise a speech at the gathering. Meanwhile, Magnolia begs Wade to write a song and perform it with her at the party.
Zoe has conflicted feelings about seeing her estranged father, world-renowned surgeon Ethan Hart, who has agreed to travel to Bluebell to perform surgery on George's father as a favor to Zoe. Fearful of losing George, Lemon decides she must befriend Zoe in order to prevent her from telling George about Lemon's affair with Lavon. Meanwhile, to celebrate the 30th anniversary of the Rammer Jammer, the owner hosts a signature cocktail contest between Wade and Shelley.
Zoe makes a romantic connection with one of her patients, Jesse, and accepts his invitation to lunch. Lemon agrees to let Magnolia plan her bachelorette party as long as she follows Lemon\'s strict instructions, but Magnolia has some more \"interesting\" plans in store for her big sister. Wade plans a hunting trip for George\'s bachelor party.
After a wild night of partying, Wade wakes up with a massive hangover, an uninvited houseguest and no memory of what happened the night before. Meanwhile, George takes an unplanned roadtrip to New Orleans, and Lemon finally confesses her troubles to her father, Brick.
Wade signs up for the Bluebell Battle in hopes of winning the five thousand dollar prize, but when he strikes out finding someone to be his race partner, he must swallow his pride and ask Zoe. Meanwhile, Rose is jumping for joy when Frederick Dean finally asks her out on a date, and George and Lemon meet with Reverend Mayfair to discuss their relationship issues.
Zoe blames herself when one of her friends faces a health crisis and she didn't notice the symptoms. With much encouragement from Lavon, Wade explores the idea of opening his own bar in Bluebell. Meanwhile, Lemon plans a romantic night for George, hoping to get their relationship back on track. Gary Cole returns as Zoe's father, Ethan Hart.
With an impending storm about to hit Bluebell, George and Lemon prepare for their wedding day. Meanwhile, taking shelter from the storm, Zoe finds herself stranded in a barn with Wade.