When Simone is transferred from St James's in a serious condition, Elizabeth forces Ric to do everything in his power to save her. The situation intensifies when Simone indicates that she doesn't want to be resuscitated if anything should go wrong in theatre. Aware that Elizabeth still blames him for his previous interference in the case, Ric must tread very carefully to ensure he does the right thing this time round.
This series is a spin-off from the long running BBC medical drama Casualty. Set in the same hospital as its sister series, this show follows the everyday lives, professional and personal, of the doctors, nurses and patients who find themselves, for various reasons, in the wards of Holby City General Hospital