Mike Barratt and his team are at crisis point when faced with a case of the deadly and contagious disease diphtheria when two Ukrainian sisters are admitted. Nick Jordan has to face his negligence hearing on the passing of Janice Alexander, which gets off to a very shaky start. Karen decides that their marriage is finished.
This series is a spin-off from the long running BBC medical drama Casualty. Set in the same hospital as its sister series, this show follows the everyday lives, professional and personal, of the doctors, nurses and patients who find themselves, for various reasons, in the wards of Holby City General Hospital