Registrar Diane Lloyd, an old girlfriend of Ric Griffin's, joins the team on Keller Ward, where preparations are nearing completion for Sam Kennedy's wedding to Ric. Owen Davis is getting more involved with Chrissy Williams. Alex Adams takes up the invitation to join the poorly-attended stag night, and Diane suggests moving to the casino next door, where Ric wagers the £20 000 cheque that Sam is giving him to clear his debts. A young man, Gary Sullivan, is admitted to Keller with abdominal pains, which Ric finds is advanced cancer, and is put in a moral dilemma when the patient asks him to disguise the fact that it predates his taking out a large life insurance policy in favor of his fiancée. Maternity deals with a young mother-to-be who is diagnosed with herpes, and the consequences for her relationship with the father.
This series is a spin-off from the long running BBC medical drama Casualty. Set in the same hospital as its sister series, this show follows the everyday lives, professional and personal, of the doctors, nurses and patients who find themselves, for various reasons, in the wards of Holby City General Hospital