The child did not survive the operation and the parents hold Sam responsible as she influenced their decision. Meyer suspends Sam for breaking his trust however Sam does not feel she is to blame and resigns. Before leaving she vows to expose Meyer as she believes his methods are flawed and have caused too many passings. Meanwhile, Janice and her baby's lives hang in the balance after a traumatic birth. Owen is shocked to discover that his daughter is admitted with severe burns due to Chrissie's babysitting.
This series is a spin-off from the long running BBC medical drama Casualty. Set in the same hospital as its sister series, this show follows the everyday lives, professional and personal, of the doctors, nurses and patients who find themselves, for various reasons, in the wards of Holby City General Hospital