At Ed's suspension hearing, Chrissie refuses to cover for him and Tom, Ric and Zubin try to separate conjoined twins. When problems arise, Tom tries to get the permission of the parents to continue but when he fails to he continues anyway which results in him having to resign. Meanwhile, Lisa is offered the position of Ward Sister on Keller.
This series is a spin-off from the long running BBC medical drama Casualty. Set in the same hospital as its sister series, this show follows the everyday lives, professional and personal, of the doctors, nurses and patients who find themselves, for various reasons, in the wards of Holby City General Hospital