The new cardiothoracic consultant Connie Beauchamp arrives and is greated by the not very welcoming attitude of Will who is not very happy that he now has a female boss. And after a day of flirting with Ric, she sleeps with him in his office after which she reveals to him that she is the new Medical Director, making her his boss.
This series is a spin-off from the long running BBC medical drama Casualty. Set in the same hospital as its sister series, this show follows the everyday lives, professional and personal, of the doctors, nurses and patients who find themselves, for various reasons, in the wards of Holby City General Hospital