The Hulks want retribution against the Leader, who is stowed away on their ship, but their plans change when they realize their old foe, Ego the Living Planet, is in danger from Ronan the Accuser and his soldiers looking to destroy him.
Hulk has long fought alone to protect a world that sees him as a monster, but his friend Rick Jones has taken it upon himself to film the world-saving exploits of Big Green and his team to change that image.
In this never before seen team up of Hulk, his cousin She-Hulk, A-Bomb, Red Hulk and Skaar, Marvel's mightiest super heroes form an eccentric family living under one roof, working together to tackle threats that are too enormous for other heroes to handle. From trying to house break their giant red pet T-Rex to stopping Ego the Living Planet from crashing into the Earth, the Agents of S.M.A.S.H. must learn to balance Hulk-sized action with everyday family-sized problems.