When Jane and Rogelio join forces to pitch a pilot, Jane is excited until she discovers a secret about her book being published. Alba and Jorge make an important decision about their future together. Rafael asks Jane to allow Luisa to meet Mateo, but she is unsure of her decision. Meanwhile, Petra and JR's relationship is once again tested.
Set in Miami, the series details the surprising and unforeseen events that take place in the life of Jane Villanueva, a hard-working, religious young Latina woman whose family tradition and a vow to save her virginity until her marriage to a detective is shattered when a doctor accidentally artificially inseminates her by mistake during a checkup. And to make matters worse, the biological donor is a married man, a former playboy and cancer survivor who is not only the new owner of the hotel where Jane works, but was also her former teenage crush.