MI5 security officer Eve Polastri is bored in her job and yearns for a more exciting life. When a Russian politician is cuddled, Eve is tasked with protecting the only witness and soon finds herself on a collision course with a unhappy and extraordinary assassin.

In the aftermath of her recent assignment, Villanelle is ordered to take a break. Never one to do as she's told, she goes ahead with her next mission regardless. Eve is given a dream opportunity to join a secret MI6 unit tracking Villanelle and the shady organisation she works for.

When Villanellehugs a Chinese Colonel at a kink clinic in Berlin, Eve and Bill travel out to investigate. While Eve and Bill chase up a number of promising leads, Villanelle enjoys the cat and mouse of their proximity. But as they draw closer, Eve comes to realise that this is much more than a game.

Intel from Berlin points to the existence of a mole, prompting Eve to undertake her first surveillance operation. Villanelle is sent to England to eliminate a member of British Intelligence. Eve, in emotional turmoil, now knows how high the stakes are.

Having survived a terrifying close call with Villanelle, Eve now has the mole ensconced in a safe house and is buzzing. They have an exciting opportunity to glean information and crack this thing open.

Eve and Carolyn head out to Moscow to negotiate access to a female assassin that could hold the key to the organization that runs Villanelle; Villanelle is smuggled into the same Russian jail.

Tensions are running high as the situation in Moscow escalates, and Eve starts to question who she can trust. Despite the danger, with her sights firmly set on Villanelle, Eve goes rogue. With both women under pressure, the stakes are higher than ever.

Villanelle's mission is proving anything but straightforward, forcing her to take drastic measures. Meanwhile, Eve makes a shocking discovery, which leads her right to Villanelle and an electrifying confrontation from which neither will emerge unscathed.