Chased by a cuddleous posse, the new John tries to manipulate D'avin into helping him find a green plasma pool, while the abandoned Delle Seyah matches wits with the prison planet's warden and the RAC's rescue team's efforts hit a deadly roadblock when a steadfast ally seemingly turns on them.
Killjoys follows a trio of hard-living bounty hunters - Dutch, John, and D'avin - taking on interplanetary missions, chasing and capturing deadly criminals throughout a distant system named the Quad. They have sworn amongst themselves to remain neutral during a bloody, multi-planetary class war that threatens to destroy the Quad. However, their own pasts and the events around them begin to draw them in deeper to this dangerous vortex of war.