Malcolm has a new light in his life: a perky classmate named Sara (whose face, in a quirky touch, is never shown). But, according to Malcolm , she's "good-looking and smart and cool. And if we went out together, it would make me happy. So therefore, it will never happen". Ah, but it doesâ-a surprising turn of events that elates the lad and perturbs his parents, especially when Malcolm goes into an academic tailspin. And it's not long before our lovesick hero admits that he's becoming "obsessive and neurotic, and a totally jealous creep".
Malcolm is a regular high school kid trying to navigate his way through life despite the various obstacles thrown in his way a complete misunderstanding of girls, the constant burden of masterminding plans to get himself and his brothers into or out of trouble, and a miserable job at the Lucky Aide not to mention a severe case of teen angst.
Although Malcolm has a genius IQ, he can't seem to make sense of the opposite sex, much less his embarrassing family. Lois is the outspoken, opinionated mom, who still manages to rule the roost even though her boys are growing wise to her crafty ways. Hal, a dad who is just a bumbling, big kid at heart, often finds himself creating more chaos than his five boys combined.