Annie Landsberg and Owen Milgrim, two strangers drawn to the late stages of a mysterious pharmaceutical trial, each for their own reasons. Annie's disaffected and aimless, fixated on broken relationships with her mother and her sister; Owen, the fifth son of wealthy New York industrialists, has struggled his whole life with a disputed diagnosis of schizophrenia.
Neither of their lives have turned out quite right, and the promise of a new, radical kind of pharmaceutical treatment - a sequence of pills its inventor, Dr. James K. Mantleray, claims can repair anything about the mind, be it mental illness or heartbreak - draws them and ten other strangers to the facilities of Neberdine Pharmaceutical and Biotech for a three-day drug trial that will, they're assured, with no complications or side-effects whatsoever, solve all of their problems, permanently.
**NOTE: Even though Netflix releases all episodes of Maniac on one day, they are portrayed on the Calendar as airing one episode a day, for ease of visualisation.
Maniac - The Lake of the Clouds Synopsis and Schedule