Tormented by a heckler on Twitter, Marc goes on a mission with his podcast guest, Dave Foley, to track down and confront the Internet troll harassing him online. In the process, Marc's cat gets sick and he has an uncomfortable encounter with his ex-wife and her new husband.
Marc discovers the source of the awful smell stinking up his house. His podcast guest, Denis Leary, calls Marc's masculinity into question, causing him to over prepare for removing the dead animal from under his house. Marc's mom sets up a meeting between him and a family friend who becomes Marc's eager new assistant.
Marc's estranged dad, Larry shows up in an RV at Marc's house with yet another foolproof scheme to get rich quick. Marc and Larry air their grievances towards each other and a power struggle ensues. Additional guest stars: Andy Kindler, Pete Holmes and Jeff Garlin.
Marc finds out from his podcast guest and friend, Illeana Douglas, that his ex-wife is having a baby. Illeana sets Marc up on a blind date with a nice girl, but he falls for a raunchy dominatrix instead.
Tired of dating younger women, Marc decides to date an age-appropriate woman he meets at a coffee shop. She's smart and sexy, but things go south when she puts Marc in the hot seat by having him interviewed on her son's podcast. Mark Duplass also guest stars.
At an AA meeting, Marc becomes a sponsor to Manny, an ex-con just out of prison. Marc finds himself in over his head while he accompanies Manny to his old haunts. Ken Jeong also guest stars.
Marc receives an explicit photo from a female fan (Nora Zehetner), who suggests a weekend of no-strings-attached sex at an out-of-town comedy festival. Marc obliges and goes through the full six stages of a relationship within a matter of two days.
Marc freaks out after learning his "Sexfest" fling plans to move too close for comfort. After Marc rejects her, she sets her sights on the next best thing and comes between Marc and his assistant Kyle.
Marc meets up with an old college friendwho has become a mainstream sell-out filmmaker. He offers Marc a dubious part in his upcoming movie. As Marc considers the part strictly for the health benefits, he pictures how his life might look had he made different choices.
Marc's former fling moves in temporarily with Marc after being evicted. She invades Marc's boundaries and tensions go through the roof. He questions her hoarding tendencies and believes she lied about being kicked out of her previous apartment. Luckily, an unexpected visitor intervenes as their fighting hits a crescendo.