Monkey makes a name for himself as a hitman in New York City while Bryce tries to reconnect with his daughter. But all that changes when Haruka arrives with Bonsai Master's sword.
Monkey, Bryce, and Haruka break protocol, demanding to know who set them up. This leads them to a mysterious Member's Only club, where an unlikely assassin aids in their mission.
Monkey tries to save Haruka, while Bryce looks for a way to speak with Iris. But when their efforts lead them to the hyper-capable Assassin's Cooperative, a greater mission emerges...
Monkey, Bryce, and Haruka struggle against an enemy with the ability to see into the future.
Monkey is unhappyly reunited with Akiko, while the rift with Bryce deepens. Meanwhile, Monkey's bonds with the Co-Op grows deeper, and Boone's tragic past comes to light.
Monkey, Bryce, Haruka, and The Co-Op visit The Shepherd's ranch estate to retrieve the final relic, but he and his wife aren't going down without a fight.
Bryce, Haruka, and Iris turn Eunice's beach house into a fortress, awaiting the Co-Op's invasion. But when Monkey shows up, it triggers a knock-down, drag-out fight.
A reluctant Bryce smuggles himself into Slyke's mind in order to rescue Monkey from a sadistic hugger known as The Hunter.
The Co-Op uses the reforged relic to unleash the full power of the natural world on New York City. It's up to our gang and a group of unlikely heroes to stop them from destroying all of humankind.
Monkey and Bryce fight Boone throughout history, and ultimately Monkey is forced to face his true origin. But just when they think they've won the day, Akiko returns to take revenge.